Rotaviruses reach late endosomes and require the cation - dependent mannose - 6 - 2 phosphate receptor and the activity of cathepsin proteases to enter the cell 3 4 Marco
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چکیده
word count: 250 13 Text word count: 7,252 14 15 These two authors contributed equally to this work. 16 Corresponding author: [email protected]. Phone: (52-777) 3291661. Fax: (52-777) 17
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Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell.
UNLABELLED Rotaviruses (RVs) enter cells through different endocytic pathways. Bovine rotavirus (BRV) UK uses clathrin-mediated endocytosis, while rhesus rotavirus (RRV) employs an endocytic process independent of clathrin and caveolin. Given the differences in the cell internalization pathway used by these viruses, we tested if the intracellular trafficking of BRV UK was the same as that of RR...
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